Yes, in general, chlorthalidone is a good choice for African Americans or people of African descent.
Experts consider chlorthalidone to be a preferred blood pressure medicine for African Americans or people of African descent. Why? Because in some studies chlorthalidone lowered blood pressure better than other medicines among people of African descent. Chlorthalidone also worked slightly better in people of African descent than in Caucasians.
Remember that every person is different and medicines do not work the same for all people. Finding the right medicine for you is like fitting a key into a lock. Not every key will fit in your lock. Even though chlorthalidone may be a good choice for people of African descent in general, you and your doctor need to work together to find the key that will work for you.